HIF1A and COVID-19: The normoxic control of HIF-1α stabilization, usually induced by angiotensin II, showed mechanisms very similar to the HIF-1α stabilization under hypoxic conditions, where H2O2 contributes to lowering the level of L-ascorbate (vitamin C) [85], a circumstance that might suggest a role of vitamin C in reducing COVID-19 exacerbation but with a complex and puzzling meaning.