Sung and colleagues reported that suppression of G9a with the UNC0638 inhibitor resulted in a decreased expression of several fibrosis markers, namely, fibronectin, Smad3, and TGF-β as well as reduced fibrotic area, increased angiogenesis, and preserved heart function in a rat model of MI [63]. This evidence concerns the gene TGFB1 and myocardial infarction.