This concept is already debated in the literature, and some hypotheses have been put forward, such as congenital virilisation birth [53], maternal PCOS, low birth weight related to disturbed fetal nutrition [54] and the enhancement of GABAergic innervation, which modifies LH secretion in GnRH-induced PCOS [55]. This evidence concerns the gene GNRH1 and polycystic ovary syndrome.