CASP3 and glioblastoma: To analyze the mode of cell death in GBM cell lines and the two most responsive GSC lines GSC 74 and GSC 240, activity levels of the pro-apoptotic protease caspase-3 were determined 24 h after the addition of varying doses of Eltanexor for GBM cell lines and 48 h a for GSCs (Figure 2).