Specifically, lipopolysaccharide-stimulated inflammation (LPS) was more consistently associated with anxiety levels in which the presence of pro-inflammatory factors such as IL-6, IL-8, IL-10, IL-18, MCP-1, MMP2 and TNF-β prevails, with respect to depressive symptoms, in which molecules such as IL-8, MCP-1 and MMP2 prevail [53,54,55,56]. This evidence concerns the gene MMP2 and Anxiety.