Regarding the role of CRP in chronic inflammatory diseases, growing evidence suggests that elevated CRP concentrations are associated with an increased risk of cardiovascular diseases (CVD), type 2 diabetes mellitus (T2DM), Alzheimer’s disease (AD), hemorrhagic stroke and Parkinson’s disease (PD); thus representing not only an excellent biomarker of chronic inflammation, but also a direct protagonist of its pathological process [23,24]. This evidence concerns the gene CRP and Parkinson disease.