Both Walsh et al., and De Franco et al., proved that renal tissue from two patients with Sjögren’s syndrome and DRTA showed complete lack of immunoreactivity for basolateral AE1 and apical H+-ATPase in intercalated cells, although there was reactivity for AE1 in blood cells captured in the tissue sample derived from these patients [41,45]. Here, SLC4A1 is linked to Sjogren syndrome.