The well-known genetic biomarkers associated with CRC are V-Ki-ras2 Kirsten rat sarcoma viral oncogene (KRAS), B-type Raf kinase (BRAF), adenomatous polyposis coli (APC), phosphoinositide 3-kinases (PI3K), phosphatase and tensin homologue (PTEN), and TP53 protein [21]. This evidence concerns the gene APC and colorectal carcinoma.