Erdemli et al., in a prospective study of 88 patients undergoing revision arthroplasty, found significant associations between the A allele at position 238 in TNFα (p < 0.0006), the 1/2 and 2/2 alleles in IL-1 RN-VNTR, IL-6, and CT genotype in GCSF3R (p < 0.02) with PJI, but no association between IL-8 and IL-17 with PJI [20]. Here, TNF is linked to juvenile polyposis syndrome.