These data matched the penetration ratios of 0.57/0.91X for Pip/Tazo 4.5 h after the end of intermittent infusions of 4/0.5 g q8h in 40 patients affected by ventilatory-associated pneumonia (VAP) [37] and 0.4–0.5/0.65–0.85X following continuous infusions of 4/0.5 g q6h in 10 VAP individuals [17]. Here, PIP is linked to ventilator-associated pneumonia.