CDKN2A and fetal growth restriction: In the livers of IUGR versus CTRL rats, we observed, via Western blot, an increased protein expression of p21WAF (+105%; p < 0.05) (Figure 12A), p16INK4a (+88%; p < 0.05) (Figure 12C) and Acp53 (+89%; p < 0.01) (Figure 12E).