Previous studies focused on the biochemical mechanisms underlying Dexmedetomidine’s neuroprotection showed that Dexmedetomidine decreased the pro-apoptotic Bcl2-associated protein expression and increased the anti-apoptotic Bcl2 protein expression in the hippocampus of rats undergoing incomplete cerebral ischemia [7,8]. This evidence concerns the gene BCL2 and Cerebral ischemia.