IL6 and colitis: The anti-inflammatory effects of MAS against colitis were shown in Figure 2F. According to Figure 2F, the secretion of proinflammatory factors (TNF-α and IL-1β and IL-6) was enhanced dramatically and the secretion of anti-inflammatory cytokines (IL-10) was decreased significantly in the colon of mice after the treatment of DSS compared to the control group (p < 0.01).