NFKB1 and allergic asthma: Another species from the same genus, i.e., Dryopteris crassirhizoma, was reported to demonstrate significant antiallergic and anti-inflammatory activities by modulating the T-helper type 1 (Th1) and T-helper type 2 (Th2) response and reducing the allergic inflammatory reaction in phorbol myristate acetate (PMA)- and A23187-stimulated HMC-1 cells via NF-κB signaling in an ovalbumin (OVA)-induced allergic asthma model [51].