Several categories of pathways and diseases with a high relevance score were considered when selecting genes of interest: “Pathways in cancer”, “PI3K-AKT signaling pathway”, “MAPK signaling pathway”, “WNT/Hedgehog/NOTCH”, “neoplasm”, “melanoma” and “abnormalities of the skin”, as well as logFC values of these genes in RNA-seq analysis. The gene discussed is AKT1; the disease is cancer.