SCNN1A and neuroblastoma: According to whole-genome expression array data for neuroblastoma (NB) cells treated with epigenetic drugs (5-Aza-dC with or without the HDACi trichostatin A) and genome-wide DNA methylation array data for NB tissue and NB cell lines, a higher methylation frequency of SCNN1A was significantly associated with poor outcome in NB [57].