A retrospective analysis from the Moffitt Cancer Center on 47 patients who received an aHSCT for TP53 mut MDS/AML, reported that patients who achieved a clearance of the TP53 mutation (NGS) at the time of aHSCT after receiving HMA treatment, had a significantly better OS than those who did not achieve clearance (median OS of 21.73 months vs. 6.44 months, p = 0.042) [74]. The gene discussed is TP53; the disease is acute myeloid leukemia.