In addition, a subpopulation of BC derivatives was recently found to express Prss56; lineage-tracing studies demonstrated that Prss56-expressing BCs have broad differentiation potential and can give rise to SCs in the nerve roots, hypodermis, and dermis, suggesting the potential of BC cells as candidates for the cellular origin of both pNFs and cNFs [31]. Here, PRSS56 is linked to breast cancer.