NF1 and malignant peripheral nerve sheath tumor: Apart from the typical ablation of tumor suppressor genes and loss-of-function of the core components for proper PRC2 function, other candidate genes have been proposed for NF1-related MPNST development, the most frequently reported ones including SOX9/10, ERBB2/3, TWIST1, FGFR, EGFR1, PTEN, BRAF, TOP2A, KIT, and PDGFRA.