In the recent classification based on molecular parameters, glioma is categorized into subtypes with isocitrate dehydrogenase (IDH) mutation (IDH mut) and codeletion of chromosome 1 short arm (1p) and chromosome 19 long arm (19q) (IDH mut-codel) or IDH mut with no 1p/19q deletion (IDH mut non-codel). This evidence concerns the gene IDH3A and central nervous system cancer.