TFF1 and colorectal carcinoma: The inverse correlation between TFF1 expression and NF-κB activity in L1-expressing cells was also demonstrated when NF-κB signaling was inhibited in L1-transfected CRC cells with an shRNA against the p65 NF-κB subunit (L1 + shp65) or by using the mutant IκB super-repressor (L1 + IκB-SR).