MMP12 and cervical carcinoma: They promote angiogenesis by the release of molecules including cyclo-oxygenase-2 and matrix metalloproteases (MMP-12, MMP-9, MMP-7, and MMP-2), which are associated with the progression and regulation of angiogenesis in cervical cancer [17].They promote epithelial to mesenchymal transition (EMT), which is the hallmark of invasion and metastasis, thus promoting cervical cancer.