Based on our findings that SREBF1 expression was affected by the cell culture conditions and chemotherapeutics, and on previous reports that a high expression of SREBF1 correlated with the progression of colon and pancreatic cancers [31,32], we aimed to investigate a potential relationship between SREBF1 expression and the survival of patients suffering from lung cancer. The gene discussed is SREBF1; the disease is familial pancreatic carcinoma.