In general, NK cells present in different solid tumors (including lung, gastric, colorectal, and head and neck cancers) are frequently limited in number and may be located within the stroma, far from the tumor nest, and with few exceptions represented by Renal Cell Carcinoma (RCC) and GIST, which are infiltrated by a significant number of NKp46+ cells [61,62,63]. The gene discussed is NCR1; the disease is renal cell carcinoma.