Furthermore, we calculated the levels of correlation between PTX3 promoter methylation using the cBioPortal dataset and found that the methylation levels of PTX3 were lower in para-cancerous normal tissues than in tumor tissues of BLCA, BRCA, COAD, HNSC, KIRC, LIHC, LUAD, LUSC, PRAD, THCA, and UCEC (Figure 5A). The gene discussed is PTX3; the disease is neoplasm.