CD274 and carcinoma: Moreover, positive PD-L1 carcinomas exhibited greater infiltration of all evaluated TIL subtypes in comparison to negative PD-L1 cases: CD3+ (25% vs. 10%; p < 0.001), CD4+ (20% vs. 10%; p < 0.001) and CD8+ (10% vs. 5%; p < 0.001).