HCG18 and posterior cortical atrophy: Interestingly, by querying the Connectivity Map (CMap) and the Comparative Toxicogenomics Database (CTD), HDACi VPA and trichostatin A were predicted as potentially effective for the treatment of PCa bone metastasis by targeting both the lncRNAs, thus reversing the high expression of HCG18 and MCM3AP-AS1 and reducing the number of HCG18- and MCM3AP-AS1-mediated M2 type macrophages) [146].