Natsuko et al. [35] reported that ALPK1 expression was positively correlated with serum creatinine level, uric acid (blood monocyte) level, C-reactive protein (blood leukocyte) level, and IL-1β in gout patients, but there was no significant correlation between ALPK1 expression and these biochemical parameters and IL-1β in the total population (patients and controls). Here, IL1B is linked to gout.