The proportions of samples with each score among cancer cells and TAMs in adenocarcinoma and SCC are shown in Figure 2E. In adenocarcinoma, the chi-squared test showed no relationship between the score for SPP1 on TAMs and age, sex, smoking status, pStage, or the presence of an epidermal growth factor receptor (EGFR) mutation (Table 2). Here, SPP1 is linked to cancer.