COX7B and neoplasm: Figure 6b shows representative pictures of the brains, with insets representing typical metastasis-positive areas. Analyses revealed a strong decrease in the number of metastases per mouse and in the metastasis-positive tumor area per slice in mice injected with 231-BR and 231-BR-2 cells lacking COX7B, compared to wild-type 231-BR and 231-BR-2 cells (Figure 6b, left and middle graphs). The opposite effects were seen in mice that received parental MDA-MB-231 cells overexpressing Cox7b compared to wild-type MDA-MB-231 cells (Figure 6b, right graphs).