KLK3 and Familial prostate cancer: Re-Biopsy, Repeated biopsy; PCa, Prostate cancer; csPCA, clinically significant prostate cancer defined as Gleason ≥ 3 + 4; PSA, prostate specific antigen; DRE, digital rectal examination; US, transrectal ultrasound; PI-RADS, The Prostate Imaging—Reporting and Data System Version 2 (PI-RADSTM v2.1).