Through a correlation analysis between TILs, clinical features, and blood indicators (inflammatory and tumor markers), the authors showed that age, menopausal status, estrogen receptor (ER), Ki-67 index, platelets, white blood cell (WBC) count, serum carbohydrate antigen 153 (CA153) levels, and lactate dehydrogenase (LDH) were associated in a linear way with the density of CD3+, CD8+, or CD4+ TILs in the TME [103]. The gene discussed is ESR1; the disease is neoplasm.