Quantification of staining intensity according to ImageJ software demonstrated that 14.0% of the area in the tumor stage IIA sample, 16.8% in tumor stage IIB, 29.8% in tumor stage IIIA, 33.0% in tumor stage IIIB, 44.6% in tumor stage IIIC, compared to 3.4% in normal tissues, was ATAD2 positive (Figure 1D, right panel). The gene discussed is ATAD2; the disease is neoplasm.