BRD2 and adenoma: Interestingly, the authors said that the decrease in miR-143-3p in the plasma may be a potential biomarker for patients with FSH/LH+ adenoma after transsphenoidal surgery, but the expression of exosome-derived miR-143-3p in FSH/LH+ samples was not significant, indicating that miR-143-3p is mainly expressed in protein-associated plasma rather than in exosomes.