Such a process was described for CRC cells, in which CAFs-exosomes with high lncRNA colorectal cancer-associated (CCAL) expression activated the Wnt/β-catenin signaling pathway through direct interaction with mRNA stabilizing human antigen R (HuR; also known as embryonic lethal vision-like protein 1, ELAVL1), thus contributing to the development of the chemoresistance of CRC cells to oxaliplatin [120]. The gene discussed is ELAVL1; the disease is colorectal carcinoma.