Some of the reported overexpressed genes in PD are also expressed in astrocytes, such as PARK2, PARK7, PINK1, LRRK2, SNCA, ATP13A2, PLA2G6, GBA, ATP13A2, F-box protein 7 (FBXO7), and vacuolar protein sorting-associated protein 35 (VPS35) [37,79]. The gene discussed is FBXO7; the disease is Parkinson disease.