In tumors, PTEN P1 acts as a bait to adsorb and degrade miRNA targeting PTEN, and actively regulates the expression of miRNA targeting PTEN, such as miR-17, miR-21, miR-214, miR-19, and miR-26 families, resulting in upregulation of PTEN gene expression and inhibition of tumor growth [147,148,149]. The gene discussed is PTEN; the disease is neoplasm.