Chen Shen et al. found that miR-15a-5p was down-regulated in GCSCs, and inhibited the stemness of GC cells by targeting ONECUT2 [115]; Yixun Lu et al. found that miR-144-3p was down-regulated in GC and combined with the 3′ untranslated region-AUACUGU of 1689–1696 of GLI2 to inhibit the stemness of GC cells [60]. The gene discussed is GLI2; the disease is gastric cancer.