As mentioned earlier, our proteomic data showed significant changes in the levels of proteins for retinitis pigmentosa (RPE65, RP2, MERTK, and RBP3), X-linked retinoschisis (RS1), CRB1-retinal dystrophy (CRB1), Usher syndrome (PCDH15), and Leber congenital amaurosis (RD3 and KCNJ13). The gene discussed is CRB1; the disease is X-linked retinoschisis.