As shown in Table 2, a distinct set of differentially expressed MAM proteins associated with retinal degeneration were found only in Type 1 diabetic rat retinas, among which are RP2, INSR, FGF2, RPE65, RBP3, RD3, GPX4, MERTK, PCDH15, CRB1, and KCNJ13. This evidence concerns the gene INSR and retinal degeneration.