SPG4 usually presents as pure HSP, but rarely, complex phenotypes are seen, including cerebellar ataxia, executive dysfunction, epilepsy, psychosis, WMHLs, arachnoid cyst of the posterior fossa, polyneuropathy, hand tremors, and amyotrophy of the hand muscles [10,15,18,19,20,21]. Here, SPAST is linked to hereditary spastic paraplegia.