CX3CL1 and schizophrenia: When considering a neurodevelopmental model of schizophrenia, MIA with LPS has been described in terms of various behavioural disturbances, including affected sensorimotor gating [12,17,18], anxiety-like behaviour [13,19], social interactions [15], exploratory or locomotor activity [19,20,21] and cognitive deficits [22,23] as well as diverse biochemical alterations in the brains of the offspring, including the CX3CL1-CX3CR1 and CD200-CD200R pairs, which are crucial in neuron–microglia communication [13,19].