The positive cell ratio of cleaved caspase-3 was 14.17 ± 0.66% in the HB98 group, 7.71 ± 0.59% in the Bartha K61 group, and 0.70 ± 0.28% in the control group (Figure 5C), which suggested that the decrease in tumor volume is correlated with the apoptosis of tumor cells. Here, CASP3 is linked to neoplasm.