CASP3 and pheochromocytoma: Porres-martinez et al. [8] reported that 1,8-cineole enhanced the expression of SOD and GSH-PX and the ratio of nuclear vs. cytoplasmic Nrf2 and inhibited the production of intracellular ROS and the activity of caspase-3, which can protect rat pheochromocytoma cells from oxidative stress induced by hydrogen peroxide.