Our results show that there was a distinct cell-specific localization and expression pattern for each of the antioxidant enzymes studied, i.e., SOD1, SOD2, CAT, GPx1, and GSR, offering protection to various germ and somatic cell populations depending on the developmental stage of the testis, i.e., adult vs. prepubertal, as well as following cessation of spermatogenesis and steroidogenesis during induced infertility with a slow-release deslorelin implant. The gene discussed is GSR; the disease is Infertility.