GNRH1 and Infertility: These findings suggest that the continued presence of an antioxidant enzyme system during GnRH superagonist-induced testicular downregulation may still serve to protect spermatogonia as well as Sertoli and Leydig cells from free radical-mediated damage during temporary infertility, perhaps contributing to the reversibility of testicular suppression and the return of normal spermatogenesis and steroid hormone production after cessation of deslorelin’s effects.