SUMO2 and nasopharyngeal carcinoma: Mo et al. found that circRNF13 promotes the stability of SUMO2 by directly binding to the 3′-UTR of SUMO2 mRNA, increases SUMO2 protein expression, and promotes the ubiquitination of GLUT1 through SUMO2, which regulates the AMPK-mTOR pathway by inhibiting glycolysis, ultimately leading to NPC proliferation and metastasis [82].