Licoricidin, another active flavonoid, inhibited the metastatic and invasive capacity of malignant PCa cells by suppressing the secretion of the matrix metalloproteinases (MMP-2, MMP-9), TIMP-1, urokinase-type plasminogen activator (uPA), and VEGF [44]. The gene discussed is MMP2; the disease is posterior cortical atrophy.