In the immune response of hybrid bamboo to Arthrodia obscura, the differentially expressed genes in the plant–pathogen interaction pathway in the early S2 stage and middle S3 stage of infection were more abundant than those in hybrid bamboo before infection, mainly calcium-dependent protein kinases (CDPKs), calmodulin (CALM), respiratory burst oxide (RbOH), heat shock protein 90 kDa beta (HSP90), pathway-related gene transcriptional activator (PtI6) and pathway-related protein 1 (PR1). The gene discussed is TMEM37; the disease is infection.