CDH1 and colorectal carcinoma: More specifically, Fn modulates E-cadherin/β-catenin signaling via its FadA (Fusobacterium adhesin A) so as to promote oncogenic and proinflammatory responses in CRC cells [8]; the same pathogen uses the lectin Fap2 to bind the tumor-cell-expressed disaccharide Gal-GalNac [9], and host cell binding and invasion leads to the secretion of the chemokines IL-8 and CXCL1 and enhanced CRC cell migration [10].