In addition, WTAP overexpression in cholangiocarcinoma induced the expression of metastasis-related genes such as cathepsin H, matrix metallopeptidase 7 (MMP7), matrix metallopeptidase 28 (MMP28), and mucin 1 (Muc1); however, the specific regulatory mechanisms have not been investigated [117]. This evidence concerns the gene WTAP and cholangiocarcinoma.