It has been shown that the overexpressed Slc7a8 gene can regulate glutamine-dependent mTOR (mammalian target of rapamycin, member of the phosphatidylinositol 3-kinase-related kinase family of protein kinases) activation in cancer, which also requires high glutamine consumption, suggesting its role in glutamine transport [16]. The gene discussed is SLC7A8; the disease is cancer.