To gain more insight into the role of NRF2 signaling in a TDP-43-based FTD model, we analyzed the expression pattern of the NRF2 antioxidant pathway in the prefrontal cortex of CaMKII-TDP-43-WT from 90-day-old transgenic mice compared to wild-type. The gene discussed is NFE2L2; the disease is frontotemporal dementia.