The proteomic screening of cancer cells treated with OA has revealed that it downregulates several factors, such as mitochondrial uncoupling protein 2 (UCP2), MMP-2, MMP-9, PKM2, superoxide dismutase 2 (SOD2), hypoxia inducible factor 1 alpha (HIF-1α), and PROX1 [62,80,81]. The gene discussed is HIF1A; the disease is cancer.